|
www.genome.gov/Pages/Research/ADHD
Attention Deficit/Hyperactivity Disorder (ADHD) is the most common
behavioral disorder in childhood, affecting 3-5% of children between the
ages of 7 and 17. Family studies suggest that there is a genetic
component to ADHD. The aim of this study is to identify ADHD
susceptibility genes, which may lead to improved diagnosis and treatment
of this disorder.
Potentially eligible families will be asked to give written consent
to participate and will be asked to complete questionnaires for each
member in the family, including a pregnancy and birth history for each
child. These take approximately 5-10 minutes to complete. In addition,
an interview will be administered to the parent of minors enrolled in
the study to determine their eligibility for being in the study. This
screening tool is computerized and will take approximately 45 minutes to
administer per child.
Once screenings are completed, a blood collection kit will be sent to
the family to take to their local medical care provider, have blood
samples drawn and sent to NIH. There is no cost to the family to
participate. We would like to enroll entire families, with both parents
and all children.
The study is completed over the phone and through the mail. No travel
to NIH is necessary. Families members will be paid $10 when blood
samples are received.
Eligibility Criteria:
Children, ages 7-17, affected with ADHD, who have at least one
full-blooded sibling who is either affected or unaffected with ADHD, and
their parents. All children enrolled must be at least 7 years old.
Exclusion Criteria:
Prematurity; neurological conditions; Cardiac surgery; Prenatal drug
exposure; Hydrocephaly;Retardation (IQ of less than 80); Known genetic
syndromes; Known CNS disorders; Known lead toxicity; Tourette Disorder;
Obsessive-Compulsive Disorder; Major Depression on both proband and
affected sibling; Pervasive Developmental Disorder; Age under 7 years
old; Autism; Other Psychoses; Post Traumatic Stress Disorder; Language
Disorder (if known); Severe Sensory Impairment (visual and hearing).
|
